THC, CBD, urumogi, ingaruka za psychoactive - birashoboka ko wunvise byibuze abashakanye niba wagerageje kumva THC, CBD, nibitandukanya nabo. Birashoboka kandi wahuye na sisitemu ya Endocannabinoid, abakira urumogi, ndetse na terepene. Ariko mubyukuri bimeze bite?
Niba ushaka uburyo bwo kumva impamvu ibicuruzwa bivamo bikubona ibicuruzwa byo hejuru kandi bya cbd ntukore kandi icyo bagomba gukora hamwe na endocannabiide, ikaze, uri ahantu heza.
Urumogi n'uruhare rwa ecs
Kugira ngo wumve THC vbd nuburyo bitugiraho ingaruka, ugomba kubanza kumva sisitemu ya Endocannabinoid (ECS), ifasha umubiri molekile molenents eshatu zingenzi: "Intumwa", kugirango imibiri yacu itangire; Abakiriye iyi molekile zirahambira; na enzymes ibasetsa.
Kubabara, guhangayika, ubushake, ingufu, imikorere yumutima, ibihembo no kugaryama, no gusinzira, no gusinzira ni bike mubikorwa byumubiri urumogi bigira ingaruka kubikorwa kuri ECS. Inyungu zishobora kubaho zubujurire ni nyinshi kandi zirimo kugabanya gutwika no kugenzura isesemi.
Ibyo thc ikora
Umuyoboro mwinshi kandi uzwi cyane wabonetse mu gihingwa cyabagibi ni Tetrahydrocannannannannannananl (thc). Ikora reseptor CB1, ibice bya ECS mubwonko buyobora gusiba. Ubusinzi bwa Thc bwerekanwe kugirango wongere amaraso kuri cortex yibanze, akarere k'ubwonko kashinzwe gufata ibyemezo, kwitabwaho, ubumenyi bwa moteri, nibindi bikorwa bishinzwe. Imiterere nyayo yingaruka za THC kuri iyi mirimo iratandukanye kumuntu.
Iyo THC ihambiriye kwakira CB1, iraterumuka ibyiyumvo bya Euphoriya biva muri ubwonko bwahembwa by'ubwonko. Urumogi rukora inzira ihebuje yo mu bwonko, ituma twumva tumerewe neza, kandi yongera amahirwe yo gusa no gusangira mugihe kizaza. Ingaruka za Thc kuri sisitemu yigihembo cy'ubwonko ni ikintu gikomeye mu bushobozi bw'urumoneya bwo gutanga ibyiyumvo byo gusinzira na euphoria.
Ibyo CBD ikora
THC iri kure yibikoresho byonyine mubumogi bigira ingaruka itaziguye kumikorere yubwonko. Kugereranya cyane ni hamwe na kannabidiol (cbd), nicyo cya kabiri kinini kiboneka mubihingwa byabaginabi. CBD akenshi irangizwa nkutari psychoactive ariko ibi birayobya kuva ikintu icyo aricyo cyose gifite ingaruka itaziguye kumikorere yubwonko ni psychoactive. CBD rwose ikora ingaruka zubururu iyo ikorana nubwonko na sisitemu yo hagati yo hagati, nkuko bivugwa ko ifite imbaraga zikomeye zo kurwanya no kurwanya imitungo.
Mugihe rero CBD rwose ari imitekerereze, ntabwo isinda. Ni ukuvuga, ntabwo bigutera hejuru. Ibyo ni ukubera ko CBD ari bibi cyane mugukora ibyakirwa CB1. Mubyukuri, ibimenyetso byerekana ko mubyukuri bibangamira ibikorwa bya reseptor ya CB1, cyane cyane imbere ya THC. Iyo THC na CBD bakorera hamwe kugirango bigire ingaruka kubikorwa bya CB1, abakoresha bakunda kumva ko ari benshi, kandi bafite amahirwe menshi yo guhura na paranoia ugereranije nigihe CBD idahari. Ni ukubera ko THC ikora reseptor CB1, mugihe CBD ibuza.
Uburyo CBD na THC basabana
Mu magambo make, CBD irashobora kurinda ubumuga bwo kumenya bujyanye no gukabya kuri thc. Inyigisho yo mu 2013 zasohotse mu kinyamakuru cyakozwe na psychormacorlogy yagaruye abitabiriye amahugurwa kandi basanga abahawe cBD ari mbere yo kwibuka cyane kurusha abarwayi bahawe ubuyobozi bw'ahantu hose bagaragaje ko CBD ishobora guhagarika ibiyobyabwenge.
Mubyukuri, hasubijwe ubushakashatsi bwa 2013 bwo kwiga hafi 1.300 byasohotse mu binyamakuru bya siyansi byasanze "CBD ishobora kurwanya ingaruka mbi za THC." Isubiramo ryerekana kandi ko dukeneye ubushakashatsi bwinshi no kureba ingaruka za CBD ku bicuruzwa bya THC mubintu byisi. Ariko amakuru asanzwe arasobanutse neza ko CBD ikunze gusabwa nkurutidote kubantu batabishaka batabishaka batwara thc cyane kandi basanga barengewe cyane.
Urumogi rusabana na sisitemu nyinshi mumubiri
THC na CBD bihuza nibindi bitekerezo byinshi mumubiri. CBD, kurugero, ifite byibuze imbuga 12 zibikorwa mubwonko. Kandi aho CBD ishobora guhuza ingaruka za THC binyuze mu kubuza reseptor ya CB1, irashobora kugira izindi ngaruka kuri Thc Metabolism kurubuga rwibikorwa bitandukanye.
Nkigisubizo, CBD ntishobora guhora kubuza cyangwa kuringaniza ingaruka za THC. Irashobora kandi kuzamura inyungu nziza z'ubuvuzi. CBD irashobora, kurugero, kuzamura ububabare bwa Thc-bitera ububabare. Thc irashobora kurwanya antiommateri na neuroppitective antioxidectant, ahanini bitewe no gukora kwakirwa kwa CB1 mukarere katugenewe ubwonko.
Ubushakashatsi bwatanzwe na 2012 bwerekanye ko CBD ikorana na Alpd hamwe na Alpha-3 (α3), intego ikomeye yo gutunganya ububabare mu mugongo, kugirango bahagarike ububabare bwa gakondo no gutwikwa. Ni urugero rwibyo bita shingiro zera ingaruka, aho urumogi rutandukanye ruhurira hamwe muri rusange gutanga ingaruka zifatika kuruta iyo unywebwe.
Ariko niyo iyi mikoranire ntabwo isobanutse neza. Mu bushakashatsi bwa Gashyantare 2019, abashakashatsi basanze imitsi yo hasi ya CBD yongereye ingaruka nkeya za THC, mugihe CBD yo hejuru yagabanije ingaruka mbi za THC.
Tegene hamwe ningaruka za Egoge
Birashoboka rwose ko zimwe mu ngaruka zizwi cyane zizwi (nko gufunga uburinganire) zirashobora kugira bike cyane byo gukora hamwe na thc, ariko, ahubwo, imisanzu igereranije molekile zidasanzwe. Ibikoresho byimiti byitwa Terpene biha urumogi uburyohe bwabo budasanzwe hamwe nimpungenge. Baboneka mubimera byinshi - nka Lavender, igiti, na hops - no gutanga impumuro yimyandikire. Tegene, niryo tsinda rinini rya phytochesical zizwi mubumogi, nanone byaragaragaye ko ari igice gikomeye cyo kugira ingaruka zidasanzwe. Ntabwo tegenenes gusa itanga urumogi uburyohe butandukanye hamwe na farama, ariko nanone bigaragara ko bashyigikiye abandi molekile zibitsina mugutanga ingaruka za physiologiya ningendo.
Umurongo wo hasi
Urumogi ni igihingwa kitoroshye hamwe nubushakashatsi buke ugereranije ningaruka zacyo n'imikoranire yumuntu - kandi turi intangiriro yo kwiga inzira nyinshi THC, kandi turi intangiriro yo kwiga inzira nyinshi dukorana kandi dusabana na ECS zacu kugirango duhindure uburyo twumva.
Igihe cya nyuma: Ukwakira-19-2021